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1

Synthesis and activity of 4,5-diarylimidazoles as human CB1 receptor inverse agonists

Christopher W. Plummer, Paul E. Finke, Sander G. Mills, Junying Wang, Xinchun Tong, George A. Doss, Tung M. Fong, Julie Z. Lao, Marie-Therese Schaeffer, Jing Chen, Chun-Pyn Shen, D. Sloan Stribling, L

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 216 KB

english, 2005

2

Pyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation

John S. Debenham, Christina B. Madsen-Duggan, Junying Wang, Xinchun Tong, Julie Lao, Tung M. Fong, Marie-Therese Schaeffer, Jing Chen Xiao, Cathy C.R.-R. Huang, Chun-Pyn Shen, D. Sloan Stribling, Laur

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 380 KB

english, 2009

3

Dihydro-pyrano[2,3-b]pyridines and tetrahydro-1,8-naphthyridines as CB1 receptor inverse agonists: Synthesis, SAR and biological evaluation

Christina B. Madsen-Duggan, John S. Debenham, Thomas F. Walsh, Lin Yan, Pei Huo, Junying Wang, Xinchun Tong, Julie Lao, Tung M. Fong, Jing Chen Xiao, Cathy R.-R.C. Huang, Chun-Pyn Shen, D.Sloan Stribl

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 894 KB

english, 2010

4

Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents

Lauren P. Shearman, D. Sloan Stribling, Ramon E. Camacho, Kimberly M. Rosko, Junying Wang, Sharon Tong, Yue Feng, Donald J. Marsh, Hong Yu, Xiaoming Guan, Stephanie K. Spann, Douglas J. MacNeil, Tung

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 500 KB

english, 2008

5

Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats

Lauren P. Shearman, Ramon E. Camacho, D. Sloan Stribling, Dan Zhou, Maria A. Bednarek, Donna L. Hreniuk, Scott D. Feighner, Carina P. Tan, Andrew D. Howard, Lex H.T. Van der Ploeg, D.Euan MacIntyre, G

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 754 KB

english, 2003

6

Discovery of N -[(4 R )-6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2 H -pyrano[2,3- b ]pyridin-4-yl]-5-methyl-1 H -pyrazole-3-carboxamide (MK-5596) as a Novel Cannabinoid-1 Receptor (CB1R) Inverse Agonist for the Treatment of Obesity

Yan, Lin, Huo, Pei, Debenham, John S., Madsen-Duggan, Christina B., Lao, Julie, Chen, Richard Z., Xiao, Jing Chen, Shen, Chun-Pyn, Stribling, D. Sloan, Shearman, Lauren P., Strack, Alison M., Tsou, Na

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.57 MB

english, 2010

7

1-Sulfonyl-4-acylpiperazines as Selective Cannabinoid-1 Receptor (CB1R) Inverse Agonists for the Treatment of Obesity

Vachal, Petr, Fletcher, Joan M., Fong, Tung M., Huang, Cathy C. R.-R., Lao, Julie, Xiao, Jing C., Shen, Chun-Pyn, Strack, Alison M., Shearman, Lauren, Stribling, Sloan, Chen, Richard Z., Frassetto, An

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

8

Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension

Bauman, David R., Whitehead, Alan, Contino, Lisa C., Cui, Jisong, Garcia-Calvo, Margarita, Gu, Xin, Kevin, Nancy, Ma, Xiuying, Pai, Lee-yuh, Shah, Kashmira, Shen, Xiaolan, Stribling, Sloan, Zokian, Hr

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 517 KB

english, 2013

9

Ghrelin Neutralization by a Ribonucleic Acid-SPM Ameliorates Obesity in Diet-Induced Obese Mice

Shearman, Lauren P., Wang, Sheng-Ping, Helmling, Steffen, Stribling, D. Sloan, Mazur, Paul, Ge, Lan, Wang, Liyang, Klussmann, Sven, Macintyre, D. Euan, Howard, Andrew D., Strack, Alison M.

Journal:

Year:

2006

Language:

english

File:

PDF, 439 KB

english, 2006

10

Rhesus monkey model for concurrent analyses of in vivo selectivity, pharmacokinetics and pharmacodynamics of aldosterone synthase inhibitors

Cai, Tian-Quan, Stribling, Sloan, Tong, Xinchun, Xu, Ling, Wisniewski, Thomas, Fontenot, Jane A., Struthers, Mary, Akinsanya, Karen O.

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2015

Language:

english

File:

PDF, 2.88 MB

english, 2015

11

[IEEE Digest of Technical Papers. PPC-2003. 14th IEEE International Pulsed Power Conference - Dallas, TX, USA (15-18 June 2003)] Digest of Technical Papers. PPC-2003. 14th IEEE International Pulsed Power Conference (IEEE Cat. No.03CH37472) - Using specific binding DNA capture elements to direct pulsed power killing of biological agents

Kiel, J., Parker, J., Manson, P., Holwitt, E., Stribling, L., Sloan, M., Morales, P., Vivekananda, J., Gonzalez, D., Tijerina, A., Alls, J.

Year:

2003

Language:

english

File:

PDF, 176 KB

english, 2003

12

SPIE Proceedings [SPIE Biomedical Optics 2004 - San Jose, CA (Saturday 24 January 2004)] Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIV - Progress in directed energy control of vectors for microbes and other cells

Bartels, Kenneth E., Kiel, Johnathan L., Parker, Jill E., Bass, Lawrence S., de Riese, Werner T. W., Holwitt, Eric A., Vivekananda, Jeeva, Gregory, Kenton W., Hirschberg, Henry, Sloan, Mark A., Stribl

Year:

2004

Language:

english

File:

PDF, 634 KB

english, 2004

13

Chronic Inhibition of Renal Outer Medullary Potassium Channel Not Only Prevented but Also Reversed Development of Hypertension and End-Organ Damage in Dahl Salt-Sensitive RatsNovelty and Significance

Zhou, Xiaoyan, Forrest, Michael J., Sharif-Rodriguez, Wanda, Forrest, Gail, Szeto, Daphne, Urosevic-Price, Olga, Zhu, Yonghua, Stevenson, Andra S., Zhou, Yuchen, Stribling, Sloan, Dajee, Maya, Walsh,

Journal:

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

14

An automated feeding and behavior monitoring system for rodents

Furlano, Elio, Augustine, Paul, Stribling, Sloan, Metzger, Joseph, Kath, Gary

Journal:

Year:

2009

Language:

english

File:

PDF, 1012 KB

english, 2009